- theory and concepts
- decision theory
- decision psychology
- probability/bayes
- preferences/values
- priority setting/ethics
- microsimulation
- calibration/validation
- approaches and applications
- decision analysis
- risk analysis
- benefit-cost analysis
- cost-effectiveness analysis
- technology assessment
- operations research
Resources Repository
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Tutorial/PrimerPublication, Teaching Resource 1980Threshold Approach to Clinical Decision Making
This classic paper provides a "tutorial" for students learning about diagnostic testing, probability revision, and …
This classic paper provides a "tutorial" for students learning about diagnostic testing, probability revision, and how to calculate thresholds for testing, treatment, and no treatment. The authors describe how a physician's estimate of the probability that a patient has a particular disease is a principal factor in the determination of whether to withhold treatment, obtain more data by testing, or treat without subjecting the patient to the risks of further diagnostic tests. Using the concepts of decision analysis,…
Probability/Bayes | Decision Analysis | Test Performance | Value of Information | Health/Medicine -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: CEA of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals
This self-directed tutorial is about a decision analytic model of Alternative Colorectal Cancer Screening Strategies …
This self-directed tutorial is about a decision analytic model of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals. This tutorial is based on the publication: Benamouzig R, Barré S, Saurin J-C et al. Cost-Effectiveness Analysis of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals. Therapeutic Advances in Gastroenterology 2021; 14. About the Alan Colowick Innovation Fund The case-based tutorials in this teaching pack were created with support from the CHDS Alan Colowick Innovation Fund, established with…
Decision Analysis | Mathematical Models | Clinical Care | Health/Medicine | Graduate | Doctoral | Professional -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: Introduction to Programming Decision Trees
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate …
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate three initial management strategies for ductal carcinoma in situ (DCIS) based on a published analysis: Soeteman DI, Stout NK, Ozanne EM et al. Modeling the Effectiveness of Initial Management Strategies for Ductal Carcinoma in Situ. J Natl Cancer Inst 2013; 105 (11): 774-781. The tutorial describes how to build the model structure, parameterize the model probabilities and outcomes based on…
Decision Analysis | Mathematical Models | Clinical Care | Health/Medicine | Graduate | Doctoral | Professional -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: Using Fire in Forest Management: Decision Making under Uncertainty
This self-directed tutorial is for a decision analytic model related to the execution and management …
This self-directed tutorial is for a decision analytic model related to the execution and management of prescribed burns within forests. This tutorial builds upon the work of the publication: Cohan D, Haas SM, Radloff DL, Yancik RF. Using Fire in Forest Management: Decision Making Under Uncertainty. Interfaces 1984; 14 (5): 8-19. Not open access. About the Alan Colowick Innovation Fund The case-based tutorials in this teaching pack were created with support from the CHDS Alan Colowick…
Decision Analysis | Mathematical Models | Environmental Health | Climate/Environment | Graduate | Doctoral | Professional -
Resource PackPublication, Teaching Resource 2022Resource Pack: Decision Analysis & Childhood Obesity
This resource pack on childhood obesity was curated by the Center for Health Decision Science …
This resource pack on childhood obesity was curated by the Center for Health Decision Science to showcase existing cost-effectiveness analyses and motivate students, educators, and others to pursue new applications of decision science methods to the public health challenge of obesity. The resource pack was motivated by the NEJM article entitled Simulation of Growth Trajectories of Childhood Obesity into Adulthood published on November 30, 2017, with CHDS co-authors Zach Ward and Stephen Resch. Citation: Ward Z, Long M,…
Cost-Effectiveness Analysis | Costing Methods | Health Outcomes | Child/Nutrition | Chronic Disease/Risk | Policy/Regulation | Clinical Care | Culture/Society | Economics/Finance | Food/Agriculture | Health/Medicine | North America -
Resource PackPublication, Teaching Resource 2018Resource Pack: Models for Health Decision Science
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to …
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to mathematical models used in health decision science (e.g., microsimulation, dynamic transmission, agent-based, etc.). Resources include overviews, guidelines, tutorials, and applications relevant to a broad range of clinical and public health topics. A decision analytic approach relies on the use of a mathematical model to formally structure the components of the decision over time. Models are particularly useful when multiple data sources…
Microsimulation | Mathematical Models | State-Transition | Dynamic Transmission | Dynamic Simulation | Climate/Environment | Economics/Finance | Health/Medicine | Science/Technology -
Tutorial/PrimerPublication, Teaching Resource 2017Bayesian Methods for Calibrating Health Policy Models: A Tutorial
This article provides a tutorial on Bayesian approaches for model calibration. It describes the theoretical …
This article provides a tutorial on Bayesian approaches for model calibration. It describes the theoretical basis for Bayesian calibration approaches as well as pragmatic considerations that arise in the tasks of creating calibration targets, estimating the posterior distribution, and obtaining results to inform the policy decision. These considerations, as well as the specific steps for implementing the calibration, are described in the context of an extended worked example about the policy choice to provide (or…
Calibration/Validation | Infectious Diseases | Health/Medicine -
Tutorial/PrimerPublication, Teaching Resource 2015Calibration of Complex Models through Bayesian Evidence Synthesis: A Tutorial
This tutorial demonstrates how to implement a Bayesian synthesis of diverse sources of evidence to …
This tutorial demonstrates how to implement a Bayesian synthesis of diverse sources of evidence to calibrate the parameters of a complex model. To illustrate these methods, the authors demonstrate how a previously developed Markov model for the progression of human papillomavirus (HPV-16) infection was rebuilt in a Bayesian framework. Transition probabilities between states of disease severity are inferred indirectly from cross-sectional observations of prevalence of HPV-16 and HPV-16–related disease by age, cervical cancer incidence, and…
Calibration/Validation | Infectious Diseases