Resources Repository
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Lesson/ModuleWeb Portal, Teaching Resource 2016Placing a Bet: New Therapy for Parkinson's Disease
This module is intended for use by business school students. It examines the decision-making process …
This module is intended for use by business school students. It examines the decision-making process at a pharmaceutical company as its chief operating officer decides whether to invest in the development and licensing of a promising treatment for Parkinson’s disease. The module is structured around a drug development case that provides students with opportunities to: (1) analyze a rich and realistic description of the complex scientific and medical results associated with a promising therapeutic molecule…
Technology Assessment | Global | Chronic Disease/Risk | Test Performance | Policy/Regulation | Business/Industry | Government/Law | Health/Medicine | Science/Technology | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Shale Gas Development
This module has been developed around the topic of the extraction of natural gas from …
This module has been developed around the topic of the extraction of natural gas from shale. This practice, commonly referred to as fracking, involves several practices that have complex and uncertain consequences. In the module, three scientific concepts are explored in order to elucidate how science is applied toward addressing real-world problems. The scientific concepts are: (1) correlation is not the same as causation, (2) hazard is not the same as risk, and (3) risk…
Risk Analysis | Global | Environmental Health | Probability/Bayes | Policy/Regulation | Business/Industry | Climate/Environment | Energy/Engineering | Government/Law | Science/Technology | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Drug-Induced Birth Defects
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth …
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth defects, the module aims to provide students with a general understanding of the following: (1) human risk factor causation as determined by epidemiologic methods; (2) the limits of non-human toxicological evidence to the assessment of causality in humans; (3) the importance of pharmacovigilance for all medications; (4) special difficulties in identifying causes of human birth defects; (5) the importance of…
Risk Analysis | Global | Chronic Disease/Risk | Health Outcomes | Evidence Synthesis | Child/Nutrition | Government/Law | Health/Medicine | Science/Technology | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
ArticlePublication 2016Essential Package of Cancer Control: Costs, Affordability, and Feasibility of an Essential Package of Cancer Control Interventions in LMIC Countries
Investments in cancer control-prevention, detection, diagnosis, surgery, palliative care-are needed in low-income and particularly in …
Investments in cancer control-prevention, detection, diagnosis, surgery, palliative care-are needed in low-income and particularly in middle-income countries, where most of the world's cancer deaths occur without treatment or palliation. To help countries expand locally appropriate services, Disease Control Priorities, 3rd edition developed an essential package of potentially cost-effective measures for countries to consider and adapt. Interventions included in the package are: prevention of tobacco-related cancer and virus-related liver and cervical cancers; diagnosis and treatment of…
Cost-Effectiveness Analysis | Global | Chronic Disease/Risk | Costing Methods | Health Systems | Health/Medicine | Science/Technology -
ReportPublication 2016Cost-Effectiveness of Mental, Neurological, and Substance Use Disorders
This report chapter reviews the available cost-effectiveness evidence for the different levels and underpinning strategies of …
This report chapter reviews the available cost-effectiveness evidence for the different levels and underpinning strategies of the mental health care system, with a focus on information generated in or for lower and middle income countries. First, the chapter reviews the economic evidence for mental health prevention and protection at the population and community levels of the health and welfare system, including legislative, regulatory, and informational measures at the public policy level (population platform), as well as…
Cost-Effectiveness Analysis | Global | Chronic Disease/Risk | Evidence Synthesis | Health Systems | Health/Medicine -
ReportPublication 2015Chapter 4: Cervical Cancer
This chapter focuses on the possibility of primary prevention of cervical cancer as a result …
This chapter focuses on the possibility of primary prevention of cervical cancer as a result of the introduction of two commercially available vaccines against human papillomavirus (HPV). Few low- and middle-income countries (LMICs) have initiated or sustained cytology-based cervical cancer prevention programs, and these countries experience very high incidence and mortality rates. Fortunately, alternative strategies to prevent cervical cancer have been investigated and extensively evaluated in these settings. The authors report findings from cost-effectiveness analyses…
Cost-Effectiveness Analysis | Global | Chronic Disease/Risk | Mathematical Models | Infectious Diseases | Health Systems | Clinical Care | Health/Medicine | Science/Technology -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Cost-Effectiveness Analysis | Global | Chronic Disease/Risk | Health Outcomes | Mathematical Models | Calibration/Validation | Infectious Diseases | Health Systems | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Lesson/ModuleWeb Portal, Teaching Resource 2014Maths and Our Health
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics …
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics in decision-making. Each pack provides videos and supplemental materials, including presentations, worksheets, and games. Topics include: “Eating Bacon Sandwiches is Bad for You!” Evaluating Risk Epidemics: Modelling with Mathematics Life Saving Maths: How Does Vaccination Work? The Economics of Health: How Do We Decide? The Test is Positive: But What Are the Odds It’s Wrong?
Decision Analysis | Global | Chronic Disease/Risk | Decision Theory | Test Performance | Mathematical Models | Infectious Diseases | Child/Nutrition | Economics/Finance | Health/Medicine | Science/Technology | Middle School | High School | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ReviewPublication 2012Modeling Preventative Strategies Against HPV-Related Disease in Developed Countries
This review article is part of a special supplement on “Comprehensive Control of HPV Infections …
This review article is part of a special supplement on “Comprehensive Control of HPV Infections and Related Diseases.” At the time of its writing, prophylactic vaccination against human papillomavirus (HPV) in pre-adolescent females had been introduced in most developed countries, supported by modeled evaluations that had almost universally found vaccination of pre-adolescent females to be cost-effective. Vaccination of pre-adolescent males had been shown to be cost-effective at a cost per vaccinated individual of ~US$400-500 if…
Cost-Effectiveness Analysis | Global | Chronic Disease/Risk | Mathematical Models | Social Determinants | Health Systems | Health/Medicine