Resources Repository
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ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Risk Analysis | Decision Analysis | Policy/Regulation | Health Systems | Dynamic Transmission | Infectious Diseases | Government/Law | Health/Medicine | Science/Technology | Global -
Resource PortalWeb Portal, Teaching Resource 2024MIDAS
MIDAS is a collaborative network of research scientists who use computational, statistical and mathematical models …
MIDAS is a collaborative network of research scientists who use computational, statistical and mathematical models to understand infectious disease dynamics and thereby assist the nation to prepare for, detect and respond to infectious disease threats. Midas focuses on research topics such as: Dynamics of emergence and spread of pathogens; Identification and surveillance of infectious diseases; Effectiveness and consequences of intervention strategies; Host/pathogen interactions; Ecological, climatic, economic and evolutionary dimensions of infectious diseases; The roles of behavior and behavioral adaptation in…
Risk Analysis | Calibration/Validation | Policy/Regulation | Health Systems | Mathematical Models | Dynamic Transmission | Dynamic Simulation | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Climate/Environment | Health/Medicine | Science/Technology | Global | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Conceptual Mapping | Quantitative Literacy -
BookPublication 1978Swine Flu Affair: Decision-Making on a Slippery Disease
This report from the Institute of Medicine, The Swine Flu Affair: Decision-Making on a Slippery …
This report from the Institute of Medicine, The Swine Flu Affair: Decision-Making on a Slippery Disease, was written to review and critique the decisions made around the 1976 swine flu threat. In 1976, a small group of soldiers at Fort Dix were infected with a swine flu virus that was deemed similar to the virus responsible for the great 1918-19 world-wide flu pandemic. The U.S. government initiated an unprecedented effort to immunize every American against…
Risk Analysis | Decision Analysis | Policy/Regulation | Health Systems | Infectious Diseases | Health/Medicine | Science/Technology | North America -
OrganizationWeb Portal 2024Agency for Healthcare Research and Quality (AHRQ)
The Agency for Healthcare Research and Quality (AHRQ) is the nation's lead federal agency for …
The Agency for Healthcare Research and Quality (AHRQ) is the nation's lead federal agency for research on health care quality, costs, outcomes and patient safety. AHRQ is the health services research arm of the U.S. Department of Health and Human Services (HHS), complementing the biomedical research mission of its sister agency, the National Institutes of Health. The agency is home to research centers that specialize in major areas of health care research, including: clinical practice…
Decision Analysis | Policy/Regulation | Health Systems | Maternal/Reproductive Health | Costing Methods | Health Outcomes | Test Performance | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | Mental Health | Injuries/Accidents | Social Determinants | Economics/Finance | Government/Law | Health/Medicine | Science/Technology | North America -
ArticlePublication 2023Simulation-Based Comparative Effectiveness Analysis of Policies to Improve Global Maternal Health Outcomes
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) …
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) to less than 70 maternal deaths per 100,000 live births by 2030, with no individual country exceeding 140. However, on current trends the goals are unlikely to be met. The authors used an empirically calibrated Global Maternal Health microsimulation model, which simulates individual women in 200 countries and territories to evaluate the impact of different interventions and strategies from 2022…
Calibration/Validation | Health Systems | Maternal/Reproductive Health | Health Outcomes | Mathematical Models | Microsimulation | Clinical Care | Health/Medicine | Global -
ArticlePublication 2023Simulation-Based Estimates and Projections of Global, Regional and Country-Level Maternal Mortality by Cause, 1990-2050
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given …
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given the many causes and frequent underreporting of maternal deaths. The authors developed a structural microsimulation model of Global Maternal Health (GMatH) for 200 countries and territories using demographic, epidemiologic, clinical and health system data synthesized from the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. The model was calibrated to empirical data from 1990 to…
Calibration/Validation | Health Systems | Maternal/Reproductive Health | Health Outcomes | Evidence Synthesis | Microsimulation | Clinical Care | Health/Medicine | Global -
Resource PackWeb Portal, Teaching Resource 2023Resource Pack: Maternal Health Models and CEA
This resource pack, curated by the Center for Health Decision Science, provides selected examples of …
This resource pack, curated by the Center for Health Decision Science, provides selected examples of modeling approaches used to conduct analyses relevant to maternal and reproductive health. Some papers focus on a particular problem (e.g., screening for prenatal syphilis, comparison of alternative strategies for safe abortion), while others explore strategies for reducing morbidity and mortality from the entire spectrum of pregnancy and childbirth-related complications. Several of the examples model the primary drivers of maternal mortality (e.g.,…
Calibration/Validation | Health Systems | Maternal/Reproductive Health | Costing Methods | Evidence Synthesis | Mathematical Models | Microsimulation | Cost-Effectiveness Analysis | Clinical Care | Health/Medicine | Science/Technology | Global | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Resource PackPublication, Teaching Resource 2021Resource Pack: Risk, Economics, and Decisions
This resource pack, curated by the Center for Health Decision Science, includes articles from the …
This resource pack, curated by the Center for Health Decision Science, includes articles from the Risk Analysis special issue “Risk Assessment, Economic Evaluation, and Decisions” honoring Professor John Evans. The special issue was guest edited by CHDS’ Deputy Director Lisa A. Robinson and builds upon a 2019 workshop organized by Ms. Robinson and CHDS faculty James K. Hammitt. Articles include: James K. Hammitt, Lisa A. Robinson. Introduction to Special Issue on Risk Assessment,…
Risk Analysis | Decision Analysis | Policy/Regulation -
Resource PackPublication, Teaching Resource 2017Resource Pack: U.S. Opioid Epidemic
Opioid misuse and addiction in the United States is an ongoing and rapidly evolving public …
Opioid misuse and addiction in the United States is an ongoing and rapidly evolving public health crisis, requiring an urgent coordinated response and innovative scientific solutions. This resource pack was curated for educators and students interested in how decision analytic methods and tools can be applied to the problem of opioid addiction.
Decision Analysis | Policy/Regulation | Health Systems | Preferences/Values | Evidence Synthesis | Mathematical Models | Cost-Effectiveness Analysis | Chronic Disease/Risk | Mental Health | Social Determinants | Economics/Finance | Government/Law | Health/Medicine | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation