Resources Repository
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ArticlePublication 2022Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face …
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face of uncertainty. This study aimed to quantify consequences of approving therapies or pursuing further research. The authors used a cohort state-transition model for hospitalized patients with COVID-19 to estimate quality-adjusted life-years (QALYs) and costs associated with multiple drug regimens and usual care. For each they assessed immediate approval, use only in research, emergency use authorization or reject. They conducted cost-effectiveness…
Benefit-Cost Analysis | Value of Information | North America | Policy/Regulation | State-Transition | Infectious Diseases | Economics/Finance | Europe -
ArticlePublication 2022Cost-Effectiveness of Masked Hypertension Screening and Treatment
The study assessed the health and economic outcomes of screening and treating masked hypertension in …
The study assessed the health and economic outcomes of screening and treating masked hypertension in U.S. adults using the Cardiovascular Disease (CVD) Policy Model, a microsimulation model. The model simulated 100,000 adults suspected of having masked hypertension (office blood pressure [BP] of 120–129/<80 mm Hg, not on antihypertensive medications, and without a history of CVD). Interventions included: usual care alone, usual care with ambulatory BP monitoring (ABPM), and usual care with home BP monitoring (HBPM).…
Microsimulation | North America | Clinical Care | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health/Medicine -
ReviewPublication 2022Systematic Review of Economic Evaluations of COVID-19 Interventions: Non-Health Impacts and Distributional Issues
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether …
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether they incorporated non-health impacts and distributional concerns. Among the 70 articles included, more than half (56%) included at least one non-health impact, although only 21% incorporated non-economic consequences. Only 17% examined subgroups of interest. The median ICER for the entire sample was $67,000/quality-adjusted life-year (QALY) (interquartile range [IQR] $9000-$893,000/QALY). Interventions including a pharmaceutical component yielded a median ICER of $93,000/QALY (IQR…
Evidence Synthesis | North America | Social Determinants | Cost-Effectiveness Analysis | Infectious Diseases | Culture/Society | Economics/Finance | Health/Medicine -
ReportPublication 2021Valuing COVID-19 Mortality and Morbidity Risks
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk …
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk reductions that builds on the U.S. Department of Health and Human Services (HHS) Guidelines for Regulatory Impact Analysis. They review the differences between COVID-19 mortality risks and the types of risks that are more commonly studied, and find that the impacts of these differences on the value of mortality risk reductions (the value per statistical life, VSL) are uncertain. They…
Preferences/Values | Benefit-Cost Analysis | North America | Policy/Regulation | Infectious Diseases | Government/Law -
ArticlePublication 2021Identifying Credible Sources of Health Information in Social Media: Principles and Attributes
Social media is widely used as a source of health information for the general public. …
Social media is widely used as a source of health information for the general public. The potential for information shared through social media to influence health outcomes necessitates action by social media platforms to enhance access and exposure to high-quality, science-based information. This paper summarizes the work of an independent advisory group convened by the National Academy of Medicine that deliberated and gathered information to develop a set of initial principles and attributes that could…
Preferences/Values | North America | Policy/Regulation | Social Determinants | Decision Psychology | Culture/Society | Education/Labor | Health/Medicine | Science/Technology -
ArticlePublication 2021Scientific Theory of Gist Communication and Misinformation Resistance
This article presents a framework for understanding how misinformation shapes decision-making, which has cognitive representations …
This article presents a framework for understanding how misinformation shapes decision-making, which has cognitive representations of gist at its core. The author discusses how the framework goes beyond prior work, and how it can be implemented so that valid scientific messages are more likely to be effective, remembered, and shared through social media, while misinformation is resisted. The distinction between mental representations of the rote facts of a message – its verbatim representation – and…
Preferences/Values | North America | Policy/Regulation | Social Determinants | Decision Psychology | Culture/Society | Health/Medicine | Science/Technology -
Online LearningVideo, Teaching Resource 2021Reporting on COVID-19 Vaccines at the Intersection of Science and Politics
Journalists play a vital role in communicating to the public about COVID-19 vaccines, and currently …
Journalists play a vital role in communicating to the public about COVID-19 vaccines, and currently under challenging circumstances. The science surrounding COVID-19 is rapidly changing, vaccines have been developed at “warp speed” using a new approach, and misinformation is on the rise. Moreover, current and historical injustices and inequities, as well as heightened political polarization, affect what information is consumed, trusted, and acted upon. This webinar offers an opportunity for members of the media to…
Preferences/Values | North America | Policy/Regulation | Social Determinants | Decision Psychology | Infectious Diseases | Culture/Society | Health/Medicine | Science/Technology -
ArticlePublication 2021Measuring the News and Its Impact on Democracy
Since the 2016 U.S. presidential election, the deliberate spread of misinformation online, and on social …
Since the 2016 U.S. presidential election, the deliberate spread of misinformation online, and on social media in particular, has generated extraordinary concern, in large part because of its potential effects on public opinion, political polarization, and ultimately democratic decision making. Recently, however, some have argued that both the prevalence and consumption of “fake news” per se is extremely low compared with other types of news and news-relevant content. Although neither prevalence nor consumption is a…
Preferences/Values | North America | Policy/Regulation | Social Determinants | Decision Psychology | Culture/Society | Science/Technology -
ArticlePublication 2021National Academies Work Helps Foster an Evidence-Based Information Environment
U.S. Surgeon General Vivek Murthy issued a public advisory on health misinformation, calling it a …
U.S. Surgeon General Vivek Murthy issued a public advisory on health misinformation, calling it a “serious threat to public health” and encouraging all Americans to help slow its spread during the COVID-19 pandemic and beyond. To that end, the National Academies have been addressing misinformation in health and science on multiple fronts and are taking steps to help cultivate a fact- and evidence-based information environment. This description was extracted from the article.
Preferences/Values | North America | Policy/Regulation | Social Determinants | Decision Psychology | Infectious Diseases | Culture/Society | Health/Medicine | Science/Technology