Resources Repository
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ArticlePublication 2018Resource Allocation in Decision Support Frameworks
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value …
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value tradeoffs from decision makers and summarizing the performance of investment options. This is done across all chosen dimensions of value, based on the weights provided by the decision makers, but comes at a cost. Currently there is no widely accepted method to suggest how to determine a budget constraint using multi-attribute models or to measure willingness to pay for incremental…
Benefit-Cost Analysis | Cost-Effectiveness Analysis | Health Systems | Priority Setting/Ethics | Health/Medicine | Global -
Resource PackPublication, Teaching Resource 2018Resource Pack: Economic Evaluation Guidelines
This resource pack includes guidelines for health economic evaluation - methods designed to identify, measure …
This resource pack includes guidelines for health economic evaluation - methods designed to identify, measure and value the incremental resources used, relative to benefits gained, of alternative interventions or policies - with the goal of improving resource allocation decisions by addressing efficiency in healthcare. The selected examples focus predominantly on the conduct of cost-effectiveness analysis. Over the past three decades, cost-effectiveness analysis has gained increasing attention from decision makers in both resource-rich and resource-poor countries.…
Benefit-Cost Analysis | Cost-Effectiveness Analysis | Health Systems | Preferences/Values | Priority Setting/Ethics | Costing Methods | Policy/Regulation | Climate/Environment | Economics/Finance | Government/Law | Health/Medicine | Global | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation -
ReportPublication 2013Decision and Simulation Modeling Alongside Systematic Reviews
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks …
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The chapter discusses the role of decision analysis and decision-analytic models in health care, specifically within the context of the current emphasis on evidence-based medicine and the proliferation of systematic reviews. It describes the types of model available…
State-Transition | Health Systems | Clinical Care | Evidence Synthesis | Dynamic Transmission | Microsimulation | Dynamic Simulation | Health/Medicine -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Probability Revision and Bayes
In this teaching pack on Probability Revision and Bayes, students are introduced to the implications …
In this teaching pack on Probability Revision and Bayes, students are introduced to the implications of imperfect information, acquire a conceptual understanding of Bayes theorem, and gain practical skills in performing probability revision. Materials include an instructor's note, videos, companion slides, a glossary, an annotated bibliography, sample exercises, and additional support. Learning Objectives Demonstrate a conceptual understanding of Bayes’ theorem and probability revision. Differentiate between test characteristics (e.g., probability of positive test given…
Probability/Bayes | Decision Analysis | Environmental Health | Test Performance | Health/Medicine | College | Graduate | Critical Thinking/Analysis | Graphics/Visualization | Quantitative Literacy -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Cost-Effectiveness Analysis III
In this teaching pack on Economic Evaluation: Cost-Effectiveness Analysis III, students are introduced to the …
In this teaching pack on Economic Evaluation: Cost-Effectiveness Analysis III, students are introduced to the different types of costs that are included in a cost-effectiveness analysis and learn how the perspective of the analysis helps to determine which costs would be included. Additionally, students learn the three basic steps to costing, identifying costs, measuring costs, and valuing costs, and become familiar with the recommendations of both the original and the more recent Panel on Cost-Effectiveness…
Cost-Effectiveness Analysis | Decision Analysis | Health Systems | Costing Methods | Evidence Synthesis | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
ArticleWeb Portal 2017PLoS Collection: Prevention, Diagnosis and Treatment of Sexually Transmitted Infections
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted …
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted infections (STIs) occur each day, incurring a very substantial burden of morbidity, mortality and additional infections. The pathogens responsible include bacteria, parasites and viruses, and intensive research is needed to address the substantial barriers to diagnosis and treatment of STIs, and the behavioral challenges of prevention. This PLOS collection, published in collaboration with WHO, focuses on global policy and systems…
Mathematical Models | Cost-Effectiveness Analysis | Health Systems | Priority Setting/Ethics | Costing Methods | Dynamic Transmission | Infectious Diseases | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Risk Analysis | Decision Analysis | Health Systems | Dynamic Transmission | Infectious Diseases | Policy/Regulation | Government/Law | Health/Medicine | Science/Technology | Global -
ArticlePublication 2017Changing the South African National ART Guidelines: The Role of Cost Modelling
This analysis was motivated by the South African Department of Health's request to assess the …
This analysis was motivated by the South African Department of Health's request to assess the cost implications of adopting sets of ART guidelines issued by the World Health Organization between 2010 and 2016.Using data from large South African ART clinics (n = 24,244 patients), projections of patients in need of ART, and cost data from bottom-up cost analyses, the authors constructed a population-level health-state transition model with 6-monthly transitions between health states depending on patients’ age,…
State-Transition | Health Systems | Clinical Care | Costing Methods | Infectious Diseases | Economics/Finance | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2017Cost-Effectiveness of Testing and Treatment for Latent TB
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve …
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. This analysis estimated health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities (e.g., diabetes, HIV infection, and end-stage renal disease). A decision analytic tree and Markov cohort simulation model was used to compare the following strategies: no testing, tuberculin skin test (TST), interferon gamma release assay…
Cost-Effectiveness Analysis | State-Transition | Health Systems | Test Performance | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Global | North America