Resources Repository
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ArticlePublication 2020Interpreting COVID-19 Test Results: A Bayesian Approach
This article considers the following question with respect to interpreting the results of polymerase chain reaction …
This article considers the following question with respect to interpreting the results of polymerase chain reaction (PCR) assays from nasal and pharyngeal swabs for COVID-19 to inform clinical decision making: "While a positive result in an acutely ill patient is straightforward, how should physicians interpret negative tests in patients with suspected COVID-19 infection?" Using an assumption of near-perfect specificity of PCR assays for COVID-19, the authors acknowledge the uncertainty of test sensitivity. They consider two clinical scenarios…
Science/Technology | Infectious Diseases | Probability/Bayes | Test Performance | Health/Medicine | Global -
ArticlePublication 2019Cost-Effectiveness of Latent TB Screening before Immigration to Low-Incidence Countries
Despite prospective migrants to countries where the incidence of TB is low receiving TB screening …
Despite prospective migrants to countries where the incidence of TB is low receiving TB screening for active infections, screening for latent TB infection before immigration is rare. The authors used discrete event simulation to evaluate the cost-effectiveness preimmigration latent TB infection screening for migrants to low-incidence countries. They calculated cost per quality-adjusted life-year gained for migrants from countries with different TB incidences. Their analysis when combined with research on sustainability, acceptability, and program implementation can…
Government/Law | Infectious Diseases | Mathematical Models | Dynamic Simulation | Cost-Effectiveness Analysis | Health/Medicine | Global -
ReportPublication 2017DCP3: Injury Prevention and Environmental Health
This report from the World Bank is the seventh volume of the Disease Control Priorities, …
This report from the World Bank is the seventh volume of the Disease Control Priorities, Third Edition (DCP3) series and focuses on injury prevention and environmental health. The burden of death and disability resulting from interpersonal violence, road traffic injuries, unintentional injuries, occupational health risks, and climate and pollution falls disproportionately on low- and middle- income countries. This report examines risk factors and offers an economic analysis of platforms to deliver cost-effective interventions to prevent…
Culture/Society | Injuries/Accidents | Costing Methods | Health Outcomes | Evidence Synthesis | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Environmental Health | Policy/Regulation | Global Governance | Climate/Environment | Economics/Finance | Health/Medicine | Global -
ReportPublication 2015DCP3: Essential Surgery
This report from the World Bank is the first volume of the Disease Control Priorities, …
This report from the World Bank is the first volume of the Disease Control Priorities, Third Edition (DCP3) series. Essential Surgery presents data on the surgical burden of disease, disability, congenital abnormalities, and trauma, as well as the health impact and economic analysis of procedures. This report identifies 44 procedures that address substantial needs, are cost effective, and are feasible to implement in low- and middle-income countries. If made universally available, these 44 procedures could…
Science/Technology | Injuries/Accidents | Costing Methods | Health Outcomes | Evidence Synthesis | Cost-Effectiveness Analysis | Health Systems | Global Governance | Clinical Care | Economics/Finance | Health/Medicine | Global -
ReportPublication 2010Priorities for the National Vaccine Plan
The authors examine the complexities of the vaccine enterprise, a fundamental component of preventive medicine …
The authors examine the complexities of the vaccine enterprise, a fundamental component of preventive medicine and public health, from research and development of new vaccines to financing and reimbursement of immunization services. The current climate, socially, economically and politically, presents challenges and opportunities to the U.S. to strengthen the existing systems of developing, manufacturing, regulating, distributing, funding, and administering safe and effective vaccines for all people. The authors present recommendations for priority actions intended to…
Science/Technology | Infectious Diseases | Evidence Synthesis | Technology Assessment | Chronic Disease/Risk | Health Systems | Policy/Regulation | Economics/Finance | Health/Medicine | North America -
Resource PackWeb Portal, Teaching Resource 2018Resource Pack: Cervical Cancer Models
This resource pack, curated by the Center for Health Decision Science, is a collection of …
This resource pack, curated by the Center for Health Decision Science, is a collection of models of HPV-related cervical cancer, differing in design, structure and features based on analytic objectives. In many ways, HPV and its related diseases represent a prototypical public health problem given the communicable and non-communicable nature of disease, opportunities for intervention along the entire disease spectrum (e.g., primary and secondary prevention, diagnosis, treatment), the varied ages at which interventions are targeted…
Science/Technology | Infectious Diseases | Mathematical Models | State-Transition | Dynamic Transmission | Microsimulation | Calibration/Validation | Dynamic Simulation | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems | Clinical Care | Business/Industry | Economics/Finance | Health/Medicine | Global -
ArticlePublication 2018Equity Impact Vaccines May Have on Averting Deaths and Medical Impoverishment
In this analysis, authors estimated the number of deaths averted and the number of cases …
In this analysis, authors estimated the number of deaths averted and the number of cases of medical impoverishment averted of ten antigens and their corresponding vaccines across income quintiles for forty-one low- and middle-income countries. The study found that vaccines administered between 2016 and 2030 would prevent 36 million deaths. Vaccines will have the greatest impact on reducing cases of poverty caused by hepatitis B, helping an estimated 14 million people avoid medical impoverishment. An…
Science/Technology | Infectious Diseases | Priority Setting/Ethics | Costing Methods | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Child/Nutrition | Global Governance | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Asia & Pacific -
Resource PortalWeb Portal, Teaching Resource 2024Millennium Mathematics Project (MMP)
The Millennium Mathematics Project (MMP), a collaboration between the Faculties of Mathematics and Education at the …
The Millennium Mathematics Project (MMP), a collaboration between the Faculties of Mathematics and Education at the University of Cambridge, is a maths education and outreach initiative for ages 3 to 19 and the general public. The focus is on increasing mathematical understanding, confidence and enjoyment, developing problem-solving skills, and promoting creative and imaginative approaches to maths. The project consists of a family of complementary programmes, including the NRICH website, Plus online mathematics magazine, Wild Maths, and…
Science/Technology | Infectious Diseases | Probability/Bayes | Test Performance | Mathematical Models | Decision Analysis | Risk Analysis | Child/Nutrition | Environmental Health | Health/Medicine | Europe | High School | College | Graphics/Visualization | Quantitative Literacy -
Tools/ModelsPublication, Teaching Resource 2017Publicly Available Software Tools for Decision-Makers During an Emergent Epidemic
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health …
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health practitioners, decision makers and researchers to plan, prepare, identify and respond to outbreaks in near real-timeframes. The aim of this research is to evaluate the range of public domain and freely available software epidemic modelling tools. Twenty freely utilizable software tools underwent assessment of software usability, utility and key functionalities. Stochastic and agent based tools were found to be highly…
Science/Technology | Infectious Diseases | Mathematical Models | Dynamic Transmission | Dynamic Simulation | Health Systems | Climate/Environment | Health/Medicine | Global | Graduate | Doctoral | Professional | Quantitative Literacy