Resources Repository
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Tutorial/PrimerPublication, Teaching Resource 2015Economic Evaluations with Agent-Based Modelling: An Introduction
This tutorial presents the basic concepts and important features of agent-based models, and provides a …
This tutorial presents the basic concepts and important features of agent-based models, and provides a case study of a simple cost effectiveness analysis of screening for an infectious disease. Agent-based modelling (ABM) is a relatively new technique, which overcomes some of the limitations of other methods commonly used for economic evaluations. These limitations include linearity, homogeneity and stationarity. Agents in ABMs are autonomous entities, who interact with each other and with the environment. ABMs provide…
Dynamic Simulation | Mathematical Models | Health/Medicine | Infectious Diseases | Graduate | Doctoral | Professional | Conceptual Mapping | Quantitative Literacy -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: Building Decision Trees
This tutorial illustrates the basic steps needed to develop decision trees in Amua using a …
This tutorial illustrates the basic steps needed to develop decision trees in Amua using a disease screening example. It details the process of how to build the structure of a decision tree, parameterize the model with probabilities and relevant outcomes (i.e., life expectancy), evaluate three alternative screening strategies in a baseline scenario, and perform one-way sensitivity analyses to assess the robustness of the results to different parameter values. Amua, the Swahili word meaning “decide”/“solve”, is…
Mathematical Models | Health/Medicine | Clinical Care | Probability/Bayes | Decision Analysis | Graduate | Doctoral | Professional -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: CEA of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals
This self-directed tutorial is about a decision analytic model of Alternative Colorectal Cancer Screening Strategies …
This self-directed tutorial is about a decision analytic model of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals. This tutorial is based on the publication: Benamouzig R, Barré S, Saurin J-C et al. Cost-Effectiveness Analysis of Alternative Colorectal Cancer Screening Strategies in High-Risk Individuals. Therapeutic Advances in Gastroenterology 2021; 14. About the Alan Colowick Innovation Fund The case-based tutorials in this teaching pack were created with support from the CHDS Alan Colowick Innovation Fund, established with…
Mathematical Models | Health/Medicine | Clinical Care | Decision Analysis | Graduate | Doctoral | Professional -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: Introduction to Programming Decision Trees
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate …
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate three initial management strategies for ductal carcinoma in situ (DCIS) based on a published analysis: Soeteman DI, Stout NK, Ozanne EM et al. Modeling the Effectiveness of Initial Management Strategies for Ductal Carcinoma in Situ. J Natl Cancer Inst 2013; 105 (11): 774-781. The tutorial describes how to build the model structure, parameterize the model probabilities and outcomes based on…
Mathematical Models | Health/Medicine | Clinical Care | Decision Analysis | Graduate | Doctoral | Professional -
Tutorial/PrimerPublication, Teaching Resource 2023Survival Extrapolation Incorporating General Population Mortality Using Excess Hazard and Cure Models: Tutorial
The study examines the utility of excess hazard (EH) methods in reducing model uncertainty when …
The study examines the utility of excess hazard (EH) methods in reducing model uncertainty when estimating long-term survival in cost-effectiveness analyses. Using a case study of breast cancer patients, standard parametric survival models were compared with EH methods incorporating general population mortality rates, with and without a cure parameter. Results showed substantial variability in survival extrapolations across standard models, while EH methods, particularly EH cure models, significantly reduced uncertainty. Long-term treatment effects approached null for…
Mathematical Models | Health/Medicine | Chronic Disease/Risk | Cost-Effectiveness Analysis | Europe -
Tutorial/PrimerPublication, Teaching Resource 2017Bayesian Methods for Calibrating Health Policy Models: A Tutorial
This article provides a tutorial on Bayesian approaches for model calibration. It describes the theoretical …
This article provides a tutorial on Bayesian approaches for model calibration. It describes the theoretical basis for Bayesian calibration approaches as well as pragmatic considerations that arise in the tasks of creating calibration targets, estimating the posterior distribution, and obtaining results to inform the policy decision. These considerations, as well as the specific steps for implementing the calibration, are described in the context of an extended worked example about the policy choice to provide (or…
Calibration/Validation | Health/Medicine | Infectious Diseases