Resources Repository
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ArticlePublication 2013Estimated Mortality Impact of Vaccinations 2011–2020 in 73 GAVI Alliance Countries
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted …
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted by the GAVI Alliance and the Bill & Melinda Gates Foundation to estimate the impact of vaccination in 73 countries supported by the GAVI Alliance. The number of deaths averted in persons projected to be vaccinated during 2011–2020 was estimated for ten antigens: hepatitis B, yellow fever, Haemophilus influenzae type B (Hib), Streptococcus pneumoniae, rotavirus, Neisseria meningitidis serogroup A, Japanese…
Mathematical Models | Dynamic Transmission | Asia & Pacific | Middle East & North Africa | Infectious Diseases | Health Outcomes | State-Transition | Microsimulation | Global Governance | Economics/Finance | Health/Medicine | Science/Technology | Sub-Saharan Africa | Latin America & Caribbean -
ArticlePublication 2011Dynamic Policies for Controlling Spread of Emerging Infections
This paper illustrates the design and implementation of a dynamic health policy for the control …
This paper illustrates the design and implementation of a dynamic health policy for the control of a novel strain of influenza, where two types of interventions are assumed to be available during the epidemic: (1) vaccines and antiviral drugs, and (2) transmission reducing measures, such as social distancing or mask use, that may be turned "on" or "off" repeatedly during the course of epidemic. A modeling approach is described for developing dynamic health policies that allow…
Mathematical Models | Dynamic Transmission | Global | Policy/Regulation | Infectious Diseases | Dynamic Simulation | Health Systems | Health/Medicine | Science/Technology -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Mathematical Models | Asia & Pacific | Middle East & North Africa | Global | Infectious Diseases | Health Outcomes | Calibration/Validation | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems | Health/Medicine | Sub-Saharan Africa | Latin America & Caribbean -
ArticlePublication 2022COVID-19 Response: The Need for Economic Evaluation
COVID-19-related policies are fraught with trade-offs. Many of these trade-offs involve dimensions that can be …
COVID-19-related policies are fraught with trade-offs. Many of these trade-offs involve dimensions that can be quantitatively weighed using economic evaluation, such as those between health and cost outcomes. Other types of dimensions, such as those involving equity or autonomy, can be harder to quantify but should be considered in a comprehensive health policy decision-making context nonetheless. The authors of this New England Journal of Medicine Perspectives article outline how methods of economic evaluation and decision…
Benefit-Cost Analysis | Global | Policy/Regulation | Infectious Diseases | Priority Setting/Ethics | Cost-Effectiveness Analysis | Economics/Finance | Health/Medicine | North America -
ArticlePublication 2020Valuing COVID-19 Mortality Risk
In this article, the author evaluates whether conventional estimates of the value per statistical life …
In this article, the author evaluates whether conventional estimates of the value per statistical life (VSL) in the United States (about $10 million) are appropriate for evaluating policies that affect risk of COVID-19. This estimate may be too large, because: (1) VSL estimates marginal values but COVID-19 risks can be non-marginal; (2) VSL is estimated for the average resident, but COVID-19 mortality is concentrated among the elderly; and (3) the pandemic has caused substantial losses…
Preferences/Values | Benefit-Cost Analysis | Global | Infectious Diseases | Government/Law -
ArticlePublication 2017Increasing Vaccination: Putting Psychological Science into Action
Vaccination is one of the great achievements of the 20th century, yet persistent public health …
Vaccination is one of the great achievements of the 20th century, yet persistent public health problems include inadequate, delayed, and unstable vaccination uptake. Psychology offers three general propositions for understanding and intervening to increase uptake where vaccines are available and affordable. The first proposition is that thoughts and feelings can motivate getting vaccinated. Hundreds of studies have shown that risk beliefs and anticipated regret about infectious disease correlate reliably with getting vaccinated; low confidence in…
Preferences/Values | Global | Policy/Regulation | Infectious Diseases | Decision Psychology | Social Determinants | Global Governance | Culture/Society | Government/Law | Health/Medicine | Science/Technology | North America -
ArticlePublication 2021COVID-19, Fake News, and Vaccines: Should Regulation Be Implemented?
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as …
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as the role of misinformation as a disincentive – especially when published by health professionals – and citizen acceptance of measures in this regard. Data from different surveys revealed a high degree of hesitation rather than outright opposition to vaccines. The most frequent complaint related to the COVID-19 vaccination was the fear of side effects. Within the Spanish and European legislative…
Preferences/Values | Global | Policy/Regulation | Infectious Diseases | Decision Psychology | Social Determinants | Culture/Society | Education/Labor | Government/Law | Health/Medicine | Science/Technology -
ArticlePublication 2021COVID-19 Infodemic: Twitter vs. Facebook
The global spread of COVID-19 is affected by the spread of related misinformation – the …
The global spread of COVID-19 is affected by the spread of related misinformation – the so-called COVID-19 infodemic – that makes populations more vulnerable to the disease through resistance to mitigation efforts. This article analyzes the prevalence and diffusion of links to low-credibility content about the COVID-19 pandemic across Twitter and Facebook. They characterize cross-platform similarities and differences in popular sources, diffusion patterns, influencers, coordination, and automation. Comparing the two platforms, authors found divergence among…
Preferences/Values | Global | Policy/Regulation | Infectious Diseases | Decision Psychology | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | North America -
ArticlePublication 2020COVID-19 Infodemic: A New Front for Information Professionals
COVID-19 emerged from Wuhan, China and has spread in 213 countries, areas, or territories around …
COVID-19 emerged from Wuhan, China and has spread in 213 countries, areas, or territories around the globe, with nearly 144,683 deaths worldwide as-of April 18, 2020. In the wake of the COVID-19 pandemic, we have witnessed a massive infodemic with the public being bombarded with vast quantities of information, much of which is not scientifically correct. Fighting fake news is now the new front in the COVID-19 battle. This article comments on the role of…
Preferences/Values | Global | Policy/Regulation | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | Science/Technology