Resources Repository
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ArticlePublication 2019Decision-Making for Universal Access to Tuberculosis Diagnosis In India
The authors evaluated the costs of centralized and decentralized testing for tuberculosis with Xpert MTB/RIF …
The authors evaluated the costs of centralized and decentralized testing for tuberculosis with Xpert MTB/RIF (Xpert), a WHO-endorsed test. They used an agent-based simulation of TB transmission in a hypothetical representative region in India to assess the impact and cost-effectiveness of various strategies to provide universal access to diagnosis and drug susceptibility testing (DST) for tuberculosis. The authors found that decentralization was most favorable compared to centralized testing when volume at decentralized facilities was high,…
Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Health/Medicine | Asia & Pacific -
ArticlePublication 2019POC Diagnosis of TB With Truenat Assay: CEA for India's Public Sector
Using a microsimulation model, the authors compared four TB diagnostic strategies for HIV-negative adults with …
Using a microsimulation model, the authors compared four TB diagnostic strategies for HIV-negative adults with presumptive TB in order to evaluate the potential cost-effectiveness of strategies that incorporate Truenat, a molecular assay that rapidly detects TB and rifampicin-resistance. They projected life expectancy, costs, incremental cost-effectiveness ratios (ICERs), and 5-year budget impact of deploying Truenat POC in India's public sector. Used at the point-of-care in India, Truenat for TB diagnosis should improve linkage-to-care, increase life expectancy,…
Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Health/Medicine | Asia & Pacific -
ArticlePublication 2019Modelling Hospital Operations from Paper Registry Data
This article, published in BMJ Global Health, aims to evaluate operations management techniques, which are …
This article, published in BMJ Global Health, aims to evaluate operations management techniques, which are underutilized in the Ethiopian health system. Previous research has outlined the limitations of paper-based patient records, but few studies have examined their potential utility for improving management of hospital operations. The authors use data collected from paper registries in an Ethiopian obstetrics ward at Addis Ababa’s Tikur Anbessa Specialized Hospital, Ethiopia’s largest university hospital, to model the ward’s operations. The…
Mathematical Models | Operations Research | Maternal/Reproductive Health | Health Systems | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2018Cost-Effectiveness of Strategies to Prevent Road Traffic Injuries in Eastern Sub-Saharan Africa and Southeast Asia: New Results from WHO-CHOICE
The authors applied a generalized cost-effectiveness analysis (GCEA) approach, applying a null reference case, in …
The authors applied a generalized cost-effectiveness analysis (GCEA) approach, applying a null reference case, in which the effects of currently implemented interventions were subtracted from current rates of burden, in order to identify the most efficient package of interventions that could be applied to Road Traffic Injuries (RTIs). They used a population model to estimate costs and effectiveness of interventions over a 100 year time frame in eastern sub-Saharan Africa and Southeast Asia. All heath…
State-Transition | Cost-Effectiveness Analysis | Injuries/Accidents | Policy/Regulation | Culture/Society | Science/Technology | Sub-Saharan Africa | Asia & Pacific -
Lesson/ModuleVideo, Teaching Resource 2018Sensitivity Analyses
This video is intended to provide an introduction to the use of sensitivity analyses to …
This video is intended to provide an introduction to the use of sensitivity analyses to test how uncertainty impacts model predicted results. Uncertainty from point estimates used for model inputs is discussed as is testing using deterministic and probabilistic sensitivity analyses. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of Veterans Affairs Health Services Research and Development group focused on cost-effectiveness analysis and…
Mathematical Models | Decision Analysis | Health/Medicine | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Evidence Synthesis Part II: Quantitative Pooling
This video is intended to provide researchers with an introduction to the second part of conducting …
This video is intended to provide researchers with an introduction to the second part of conducting a meta-analysis: quantitatively pooling. The goal of this meta-analysis is to synthesize multiple published estimates from parameters of interest (such as disease-related mortality or the efficacy of a treatment) into a single input for use in a decision model. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of…
Mathematical Models | Evidence Synthesis | Health/Medicine | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Evidence Synthesis Part I: Systematic Literature Review
This video is intended to provide researchers with an introduction to the first part of …
This video is intended to provide researchers with an introduction to the first part of conducting a meta-analysis: a systematic literature review. The goal of this meta-analysis is to synthesize multiple published estimates from parameters of interest (such as disease-related mortality or the efficacy of a treatment) into a single input for use in a decision model. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the…
Mathematical Models | Evidence Synthesis | Health/Medicine | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Estimating Transition Probabilities for a Model
This video is intended to provide a discussion on various methods for deriving probabilities that are …
This video is intended to provide a discussion on various methods for deriving probabilities that are needed for decision models. Presented are the concepts of literature based Odds Ratios and Relative Risks, which need to be transformed into probabilities, how to deal with probability estimates from time frames not relevant to the model in question, and how to derive probabilities from published summary statistics. This lecture is aimed at the researcher who is interested in operationalizing…
Mathematical Models | Probability/Bayes | Evidence Synthesis | Health/Medicine | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018An Overview of Decision Analysis
This video is intended to provide high-level overview of the field of decision analysis and …
This video is intended to provide high-level overview of the field of decision analysis and presents topics that include: why engage in decision analysis; what are the differences between cost-effectiveness analysis, cost-utility analysis, cost-benefit analysis, and budget impact analysis; and different ways to conduct a decision analysis – such as modeling or measuring alongside a clinical trial. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the…
Mathematical Models | Decision Analysis | Cost-Effectiveness Analysis | Health Systems | Health/Medicine | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy