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EditorialPublication 2020Interpreting Diagnostic Tests for SARS-CoV-2
This viewpoint describes how to interpret two types of diagnostic tests commonly used for SARS-CoV-2 …
This viewpoint describes how to interpret two types of diagnostic tests commonly used for SARS-CoV-2 infections – reverse transcriptase-polymerase chain reaction (RT-PCR) and IgM and IgG enzyme-linked immunosorbent assay (ELISA) – and how the results may vary over time. False-negative results mainly occurred due to inappropriate timing of sample collection in relation to illness onset and deficiency in sampling technique, especially of nasopharyngeal swabs. Specificity of most of the RT-PCR tests is 100% because the…
Evidence Synthesis | Test Performance | Infectious Diseases | Health/Medicine | Science/Technology | Global -
ArticlePublication 2016Spectrum Effect in Tests for Risk Prediction, Screening, and Diagnosis
This article discusses the impact of the spectrum effect on measures of test performance, and …
This article discusses the impact of the spectrum effect on measures of test performance, and its implications for the development, evaluation, application, and implementation of such tests. The authors describe this effect as the variation between settings in performance of tests used to predict, screen for, and diagnose disease among different population subgroups. They emphasize that a test developed in a population with a higher prevalence of disease (or at higher risk) will typically have…
Evidence Synthesis | Test Performance | Clinical Care | Health/Medicine | Science/Technology -
Online LearningNone, Teaching Resource 2015Diagnostic Test Accuracy (DTA) Reviews: A Pathway
These video cases are part of an introductory series developed by Cochrane Screening & Diagnostic …
These video cases are part of an introductory series developed by Cochrane Screening & Diagnostic Test Methods Group to support authors in the production of systematic reviews of diagnostic test accuracy (DTA). Each resource is designed to be a stand-alone learning unit, although they are presented as a progressive learning pathway. Users can access the resources in any order, although those not familiar with Cochrane DTA Reviews may find it most productive to work through…
Evidence Synthesis | Test Performance | Health/Medicine
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