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ReportPublication 2017Clinical Practice Guideline Implementation Strategies: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
This report presents evidence on effective strategies to enhance the adoption of clinical practice guidelines …
This report presents evidence on effective strategies to enhance the adoption of clinical practice guidelines from the published literature. This report was produced as part of a larger effort to update existing clinical practice guidelines on cholesterol, blood pressure, and overweight/obesity that the National Heart, Lung, and Blood Institute convened in 2008. The authors conducted a systematic review on 4 questions focused on the adoption and effectiveness of 4 interventions: (1) reminders, (2) educational outreach…
Evidence Synthesis | Cost-Effectiveness Analysis | Chronic Disease/Risk | Clinical Care | Health/Medicine | North America -
ArticlePublication 2017Benefit and Harm of Intensive Blood Pressure Treatment: Derivation and Validation of Risk Models Using Data from the Sprint and Accord Trials
Intensive blood pressure (BP) treatment can avert cardiovascular disease (CVD) events but can cause some …
Intensive blood pressure (BP) treatment can avert cardiovascular disease (CVD) events but can cause some serious adverse events. The authors sought to create risk calculators to estimate individual patients’ chances of benefit and harm from intensive treatment. They developed statistical models of cardiovascular events and serious adverse events from individual participant data from the Systolic Blood Pressure Intervention Trial (SPRINT) of intensive blood pressure treatment (N = 9,069 with complete covariate data) and validated them…
Evidence Synthesis | Probability/Bayes | Health Outcomes | Chronic Disease/Risk -
ArticlePublication 2017Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older
Recent guidelines recommend a systolic blood pressure (SBP) goal of less than 150 mm Hg …
Recent guidelines recommend a systolic blood pressure (SBP) goal of less than 150 mm Hg for adults aged 60 years or older, but the balance of benefits and harms is unclear in light of newer evidence. The purpose of this study was to systematically review the effects of more versus less intensive BP control in older adults. Authors reviewed 21 randomized, controlled trials comparing BP targets or treatment intensity, and 3 observational studies that assessed…
Evidence Synthesis | Health Outcomes | Chronic Disease/Risk | Health/Medicine | North America -
GuidelinesPublication 2017Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults
In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisory Council recommended that the …
In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisory Council recommended that the NHLBI focus specifically on reviewing the highest-quality evidence and partner with other organizations to develop recommendations. Accordingly, the ACC and AHA collaborated with the NHLBI and stakeholder and professional organizations to complete and publish four guidelines in the domain of cardiovascular health, including this guideline. In 2014, the American College of Cardiology (ACC) and American Heart Association (AHA), in partnership…
Evidence Synthesis | Health Outcomes | Test Performance | Chronic Disease/Risk | Health Systems | Health/Medicine | North America | Europe -
ArticlePublication 2017Personalizing the Intensity of Blood Pressure Control, Modeling the Heterogeneity
The Systolic Blood Pressure Intervention Trial (SPRINT) suggests that, on average, hypertensive patients at high …
The Systolic Blood Pressure Intervention Trial (SPRINT) suggests that, on average, hypertensive patients at high cardiovascular risk would have less cardiovascular morbidity and mortality but higher treatment-related adverse events with an intensive blood pressure treatment strategy as compared with a standard blood pressure treatment strategy. Applying these population-level results to individual patients is challenging, as each patient may have different benefits and risks than the average patient in SPRINT. Using patient-level data from SPRINT, the authors developed…
Evidence Synthesis | Probability/Bayes | Health Outcomes | Chronic Disease/Risk | Health Systems | Health/Medicine | Science/Technology | North America -
GuidelinesPublication 2017Summary: 2017 Guideline for Management of High Blood Pressure in Adults
This report from the American College of Cardiology/American Heart Association Task Force on Clinical Practice …
This report from the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines provides a detailed summary of the 2017 Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults. Sections: Important Statistics Diagnosing Hypertension Measurement of BP Patient Evaluation and History Hypertensive Crises: Urgency vs Emergency Laboratory Tests and Other Diagnostic Procedures Out-of-Office Monitoring of BP Masked and White Coat Hypertension Treating Hypertension Blood Pressure…
Evidence Synthesis | Chronic Disease/Risk | Social Determinants | Health Systems | Health/Medicine | Science/Technology | North America | Europe
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